Anti-androgen treatments: what they do and who they help

Anti-androgens block or reduce the effect of male hormones (androgens) such as testosterone. That sounds technical, but it matters because those hormones influence acne, unwanted hair, prostate growth, and some forms of hair loss. If you’re dealing with persistent acne, female-pattern hair growth (hirsutism), prostate cancer, or planning hormone therapy, anti-androgens are often part of the conversation.

Common anti-androgens and when they’re used

There are several kinds of anti-androgens. Each works a bit differently and is chosen based on the condition being treated.

Spironolactone — widely used in women for acne and hirsutism. It blocks androgen receptors and lowers androgen production. Doctors often prefer it for hormonally driven acne when birth control alone isn’t enough.

Finasteride and dutasteride — these block the enzyme that converts testosterone into DHT, a stronger androgen. You’ll see them for male-pattern hair loss and for reducing prostate size. They are usually for men, though finasteride is sometimes off-label in other settings.

Flutamide, bicalutamide, and cyproterone acetate — stronger anti-androgens used mainly in prostate cancer or in complex endocrine cases. Some carry higher risks and need specialist oversight.

Safety, side effects, and buying tips

No drug is risk-free. Common side effects include reduced libido, erectile changes, breast tenderness or enlargement, and fatigue. Spironolactone can raise potassium levels; finasteride can affect sexual function; some older anti-androgens can impact the liver. That’s why baseline tests (like liver function and potassium) and follow-up checks matter.

Pregnancy warning: many anti-androgens can harm a developing fetus. Women who can get pregnant must use reliable contraception and follow their doctor’s guidance closely.

Thinking of buying online? Only order prescription anti-androgens from licensed pharmacies that require a valid prescription, show clear contact information, and have a pharmacist available. Avoid sites that offer prescription drugs without a prescription, use unclear packaging, or have unrealistic prices. When in doubt, call your local pharmacy or ask your prescriber for a trusted online option.

If you’re curious about alternatives for skin or hair conditions, our related article on acne options (including spironolactone) can help you compare choices and side effects. For hormone therapy or cancer care, see a specialist — these drugs are powerful and need careful monitoring.

Quick checklist: confirm the diagnosis with your clinician, review tests (LFTs, electrolytes), understand pregnancy risks, and buy from licensed pharmacies only. That small checklist keeps you safer and helps the medicine do what it’s supposed to do.

Questions about a specific drug or how these treatments might fit your situation? Talk with your healthcare provider — they can match the right anti-androgen to your needs and set up safe monitoring.